During anaphylaxis, the priority treatment is:

During anaphylaxis, the most critical and immediate intervention is the administration of epinephrine. This hormone has several vital effects that counteract the severe symptoms of anaphylactic shock. It acts quickly to constrict blood vessels, leading to increased blood pressure, alleviates airway swelling by relaxing bronchial smooth muscle, and reduces capillary permeability, which helps prevent further fluid leakage and swelling.

Antihistamines, while helpful in managing allergic reactions, do not address the life-threatening aspects of anaphylaxis quickly enough, as they take longer to exert their effects compared to epinephrine. Seeking medical consultation is also important but does not provide immediate treatment for the acute life-threatening condition at hand. Applying ice to allergic reaction sites may be beneficial for localized reactions but is ineffective for the systemic symptoms associated with anaphylaxis. Therefore, immediate administration of epinephrine is essential to stabilize the patient and prevent progression to more severe complications.